A simple method for C-6 modification of guanine nucleosides
نویسندگان
چکیده
منابع مشابه
A simple method for C-6 modification of guanine nucleosides.
A facile method for the introduction of various substituents at the C-6 position of guanosine and 2'-deoxyguanosine is reported. In a simple, 1-step transformation, tert-butyldimethylsilyl protected guanosine and 2'-deoxyguanosine were converted to the O(6)-(benzotriazol-1-yl) derivatives via reaction with 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and 1,8-...
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ژورنال
عنوان ژورنال: Organic & Biomolecular Chemistry
سال: 2009
ISSN: 1477-0520,1477-0539
DOI: 10.1039/b905298d